DERRY firm GoWalkTalk which develops management software for healthcare workers has set up an office in Boston.
It represented one success of an economic link between Massachusetts and the north-west of Ireland.
Donegal firm Gartan Technologies also formed a partnership with US company Adashi Systems.
GoWalkTalk's new Boston office was announced by the city's mayor Martin Walsh at the recent Golden Bridges conference.
He said the investment provided evidence of a positive partnership arrangement with Massachusetts and the north-west region of Ireland.
The Ireland North West delegation, the first of its kind to travel to Massachusetts, was led by the Derry City and Strabane District Council’s Mayor Hilary McClintock and the Cathaoirleach of Donegal County Council Terence Slowey among other officials, colleges and 17 businesses.
Derry and Strabane Council chief executive John Kelpie said: “We told delegates about our unique offering and the fact that Ireland North West, that includes the fourth largest city on the island of Ireland, is a very attractive location for international business partnerships because of its hugely talented skills base, competitive operating costs, advanced telecommunications infrastructure and excellent education and business linkages.
"A key selling point for us was our unique location and our close connectivity to Europe, our very youthful and talented population, and excellent skills base.
“We were very forthright about our ambitious plans for the future and told them about how we are investing multi-millions of pounds in our road, rail and air infrastructure and connectivity over the next five to 10 years, that will see the expansion of our university, the development of a graduate medical school and major redevelopment of the city sites including investment in housing, office and retail space and leisure service provision."
