Whilst Guns 'n' Roses, Elton John, Lizzo and Artic Monkeys may be headlining the Pyramid Stage, there are plenty of Irish acts performing across the weekend.
Whether you are one of the 210,000 people bathing in the sunshine and mud in Worthy Farm, Somerset, or dancing along in your living room to the BBC coverage, here are all the Irish acts you need to know about and what stage they are playing on.
FRIDAY JUNE 23
The Mary Wallopers
Stage: Acoustic
Time: 15:00 - 15:40
Contemporary Irish folk music group based in Dundalk, who deliver their music in a rabble-rousing style.
Ezra Williams
Stage: Bread and Roses
Time: 18:00-18:40
Cork born Indie songwriter and musician. Their shoegazey 2020 single My Own Person drew in fans after featuring in the coming-of-age Netflix hit Heartstopper, with its gentle melody and heart-wrenching lyrics.
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Gavin James
Stage: Acoustic
Time: 18:30-19:30
James won Ireland's answer to the Mercury (the Choice Music Prize for Song of the Year). The Dubliner now has a huge following with two billion streams.
Kettama
Stage: The Levels
Time: 19:30 - 21:00
Hard hitting house
The Saw Doctors
Stage: Acoustic
Time: 21:30-22:45
The Co Galway rockers, Irish who returned to touring last winter following a five-year break headline the Acoustic Stage.
OR:LA
Stage: The Wow
Time: 01:30-03:00
Derry-born genre-spanning DJ
SATURDAY JUNE 24
Clare Sands
Stage: Acousitc
Time: 11:30 - 12:00
The Newry based singer weaves traditional roots with contemporary sounds.
Sharon Shannon Trio
Stage: Acoustic
Time: 15:00-15:40
The Murder Capital
Stage: Woodsies
Time: 15:15-16:00
Dark, intense introspective Dubliners.
Glen Hansard
Stage: Acoustic
Time: 20:00-21:00
Academy-Award winning Irish singer-songwriter and principal vocalist/guitarist for the bands, The Frames and The Swell Season.
Annie Mac
Stage:San Remo
Time: 22:00-23:45
The Dublin DJ and author is the Queen of club culture.
Max Cooper
Stage: The Lonely Hearts Club
Time: 22:30-00:00
Electronica - techno producer
SUNDAY JUNE 25
The Love Buzz
Stage: Woodsies
Time: 11:15-12:00
Cranked up psychadelic pogo punk.
John Francis Flynn
Stage: The Park State
Time: 11:30-12:15
Traditional folk singer and multi-instrumentalist.
Cara Dillon
Stage: Avalon
Time: 13:55-14:50
Multi award-winning Dungiven folk singer, whose new album Coming Home, is out next year.
Gilbert O'Sullican
Stage: Acoustic
Time: 20:00 - 21:00
Chart-topping singer-songwriter whose melodic craftsmanship and surrealist humor ensures his career that began in 1970 continues to shine.
Saoirse
Stage: The Levels
Time: 23:30-00:10
Unpredictable and cheeky mixed style techno, Dub, house, electro, garage