The Moira Road in Lisburn is closed in both directions on Monday evening due to a car crash close to the junction with Ballinderry Road.
Emergency services are at the scene and motorists are advised to seek an alternative route.
A PSNI spokesperson said: “Motorists are advised that the Moira Road, Lisburn is currently closed in both directions close to the junction with Ballinderry Road, due to a road traffic collision.”
“Police are at the scene alongside emergency services colleagues. Please seek an alternative route for your journey. ”