Tyrone haven't picked up a single point on the road this season - and Monaghan's record in relegation battles at Clones could add to the Red Hands' away woes this weekend.
Darragh Canavan is expecting another defiant stand from the Farney men in Sunday's crunch tie, a must-win for both sides.
With the two neighbouring counties firmly entrenched in the Division One drop zone on four points each, the implications stemming from the result of this enticing Ulster derby are stark.
"They always seem to get points when they need them most and that is going to leave them a very dangerous opponent as they are in the same boat as us," said Canavan, a star of Tyrone's victory over Kerry.
"Hopefully we can go to Clones and put in a performance like that again, and if we can keep that up and keep working hard I think that we will be there or thereabouts.
"You can't beat an Ulster derby too, those are the games that you want to play in and as I said they are a tough team that are very honest and difficult to beat and no doubt it will be similar this time around again especially as both sides need the points.
"There is never much between Tyrone and Monaghan when they meet at senior level and its likely to be like that again."
The Red Hands go into the St Tiernach's Park clash on the back of a morale-boosting victory over the All-Ireland champions, while Monaghan are looking to bounce back from defeat to Galway.
"We needed to win big-time, as the table wasn't looking that good for us. We know that we still have a long way to go, it is only one game and hopefully we will have a long year ahead and it's a good starting point I suppose but it's just two points."
Ace attacker Canavan feels that much of the criticism that ensued from defeats to Roscommon, Galway and Mayo was unfair.
"We felt that we had left a lot of scores behind us in previous games. We did a lot of bad stuff in those defeats but we did good stuff as well so we just knew that if we could get one game where we had a wee bit of luck that things would go our way and thankfully things fell into place for us."
In the closing stages of the Healy Park win over Kerry, the Errigal Ciaran clubman was joined in attack by his younger brother Ruairi, who fired over a couple of crucial scores.
Others also came off the bench to help the home side over the line, demonstrating the depth of the current Tyrone squad.
"We all know that modern football is more than a fifteen man game, as you need boys coming off the bench and making an impact and we had that, and it was needed with everybody playing their part."
And character is another valuable Red Hand trait, evidenced by the manner in which they responded after conceding goals to the Kingdom early in both halves.
"It showed the character within the squad to bounce back from conceding those two goals but that was perhaps down to the support as well as they could have got on our backs and gave us a bit of stick but they stood with us and we kept at our plan and worked hard and I felt that we deserved the win.
"We were able to pull away and keep them at arm's length and it was a good response to conceding the second goal especially."
